The CELI•VITES Blood Health formula is a superior targeted solution for the gluten free lifestyle. It is scientifically formulated to include the highest quality forms of vitamins and minerals available. The ingredients in our Blood Health formula allow for maximum absorption and utilization.
Each ingredient contained within the Celi•Vites supplements was purposefully selected. To learn more about each ingredient, click the tabs below.
The iron in our Blood Health formula is in chelated form, ferrous bisglycinate (Ferrochel®), with remarkable bioavailability of up to 75%. This form of iron is absorbed up to three times better than ferrous sulfate. Ferrochel® is safe, as with other forms of iron, absorption is inversely correlated with hemoglobin levels (hemoglobin is a proxy for iron stores in the blood). Ferrochel® is also easy on the digestive system; When 30 mg of ferrous bisglycinate was given for 8 weeks there were zero digestive complaints.
Giorgini E. et al. (2001) The use of sweet rolls fortified with iron bis-glycinate chelate in the prevention of iron deficiency anemia in preschool children. Arch Latinoam Nutr 51(1 Suppl 1):48-53. PMID:11688082
Pineda O. and Ashmeda H.D. (2001) Effectiveness of treatment of iron-deficiency anemia in infants and young children with ferrous bis-glycinate chelate. Nutrition 17(5):381-384. PMID:11377130
Pineda O. et al. (1994) Effectiveness of iron amino acid chelate on the treatment of iron deficiency anemia in adolescents. J Applied Nutr 46:2-13.
Vitamin B12 is necessary for red blood cell formation and neurological function. Those suffering from malabsorption due to celiac or other intestinal diseases may be deficient in Vitamin B12. Blood Health by Celi•Vites provides 100% of the daily value as the active, Body Ready or coenzyme form, methylcobalamin.
Leishear K. et al. (2012) Relationship between vitamin B12 and sensory and motor peripheral nerve function in older adults. J Am Geriatr Soc 60:1057-63. PMID: 22690982
Folate is important for red blood cell development and in the regulation of homocysteine. Adequate folate supports healthy fetal development and during lactation it supports the developing infant. 100% of the daily value for folic acid is provided as [6S]-5-methyltetrahydrofolate (Quatrefolic®) or 5-MTHF. This is the coenzyme form of folic acid bypassing the necessity of metabolism by the body. In a clinical study with 144 women, the change in plasma and red blood cell folate concentration over time was greater when administered 5-MTHF than folic acid. Due to genetic variation, some people cannot convert folic acid into 5-MTHF.
Lamers Y. et al. (2006) Red blood cell folate concentrations increase more after supplementation with [6S]-5-methyltetrahydrofolate than with folic acid in women of childbearing age. Amer J Clin Nutr 84:156-61. PMID:16825690
100% of vitamin B2 is provided as riboflavin 5’-phosphate, the active coenzyme form. Riboflavin, or vitamin B2, is required for metabolism of homocysteine; specifically, it is required as an enzymatic cofactor for methylenetetrahydrofolate reductase (MTHFR). Approximately 12% of healthy white people have a genetic variant of MTHFR (677C-T, thermoliable or TT genotype) that is less active. Evidence from in vitro studies suggests that reduced activity of MTHFR is due to instability of the interaction with its riboflavin cofactor. In a clinical study, among those with the 677C-T genotype, those in the lowest tertile of riboflavin had higher levels of plasma homocysteine, a risk factor for development of coronary artery disease. The authors conclude that in addition to folate, riboflavin requirements should be considered by government sponsored food fortification programs to prevent hyperhomocysteinemia*. Currently there are no governmental requirements for fortification of gluten free cereal and grain products.
*McNulty, H. et al. (2002) Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status: implications for riboflavin requirements. Am J Clin Nutr 76:436-41. PMID: 12145019
To increase iron absorption and utilization, 200% of the daily value of Vitamin C is provided as PureWay-C®, an advanced form. It has long been known that vitamin C facilitates uptake of iron from the diet. It has recently been reported that vitamin C increases cellular uptake of iron bound to transferrin, a protein that carries iron within the blood stream.
Lane D.J.R., et al. (2013) Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism. Biochim Biophys Acta 1183:1527-1541. PMID: 23481043